A member asked:

I have shingles. can i mix valtrex (valacyclovir) and prednisone. dr today told me to stop prednisone. do u concur? thank you

2 doctors weighed in across 2 answers

Steroids and Zoster: Shingles is caused by the Varicella Zoster Virus. Defense against any viral infection depends on a healthy, intact immune system to rid the body of the infection. Shingles is no exception, and I have personally seen it be so severe in people without normal immune systems. Prednisone weakens precisely the part of the immune system that protects against viruses. Taking it can make shingles worse.

Answered 3/21/2015

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Dr. Matt Wachsman answered

Specializes in Internal Medicine

Can't say: Without an actual examination, I cannot give specific medical advice on your particular health, but steroids are given to prevent long term chronic pain (use brief; data not great that it works). Valtrex gets rid of virus; use is 1-2wk Might be reasons NOT to use a lot of Prednisone (diabetes for example).

Answered 6/30/2014

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