A 53-year-old member asked:
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For an aldosterone deficiency doctors will prescribe fludrocortisone acetate; is it the same as aldosterone?

1 doctor answer
Dr. Thomas Knecht
30 years experience in Endocrinology
No: Hi. No, fludrocortisone is not chemically identical to aldosterone (although many similarities), but it selectively activates the mineralocorticoid (aldosterone) receptor, so serves the purpose of aldosterone.
Answered on Jul 5, 2014

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Related questions:

A 56-year-old member asked:
Dr. Thomas Knecht
30 years experience in Endocrinology
No & yes: Hi. No, they're chemically not the same, but fludrocortisone is an aldosterone agonist with specificity for the aldosterone receptor that has better s ... Read More
A 24-year-old male asked:
Dr. Thomas Knecht
30 years experience in Endocrinology
Need whole story: Hi. Do you have Addison's or any other cause of (partial) adrenal insufficiency? You only need Florinef (fludrocortisone) for primary adrenal insuffic ... Read More
A 29-year-old male asked:
Dr. Rebecca Gliksman
37 years experience in Internal Medicine
Florinef: Why were you given Florinef? if to assess Conns syndrome (adrenal adenoma) it would lower aldosterone in the normal patient but not the ill pa ... Read More

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