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A 50-year-old member asked:

Is fludrocortisone acetate the same as aldosterone? any answer appreciated.

2 doctor answers2 doctors weighed in
Dr. Thomas Knecht
A Verified Doctoranswered
undefined 31 years experience
No & yes: Hi. No, they're chemically not the same, but fludrocortisone is an aldosterone agonist with specificity for the aldosterone receptor that has better stability and activity profiles than aldosterone. So functionally, they're kinda the same.
Dr. Clarence Grim
Endocrinology 57 years experience
FLUDROCORTISONE: No Flu is related chemically to aldo but not the same. It is used as aldo in those who do not make enough due to disease of the adrenals or having had both adrenals taken out. It can cause high BP and low K if taken in excess. I specialize in aldo problems and run a Yahoo group for pts with hyperaldosteronism. Happy to help if you need more info.

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Last updated Jan 30, 2020

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