A member asked:

What is the difference between ms and depression types of fatigue? how it feels like to have fatigue if you have ms or a simple depression?

3 doctors weighed in across 3 answers
Dr. Bernard Seif answered

Specializes in Clinical Psychology

Clinical depression: Can manifest in extreme fatigue. Difficult to get out of bed, on the couch all day, etc. However, there are others conditions that can cause these symptoms. Please visit you doc and perhaps he/she can check your thyroid and other hormones, blood sugar, etc. Please put ms at the bottom of your list and try not to let your mind run away with problems that may not exist. Called "catastrophizing.

Answered 4/26/2014

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Dr. Chad Hagans answered

Specializes in Clinical Psychology

Check Your Mood: Although there can be overlap between them, there is a difference between physical fatigue and depression, in that the latter (depression) is typically accompanied by a depressed mood -- feeling down, blue, sad, etcetera. To help you distinguish between fatigue and depression, you may wish to complete the following questionnaire and calculate your score: http://drjeremybarowsky.Com/site/wp-conte.

Answered 3/2/2016

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MS fatigue: In MS, fatigue is almost constant, not associated with exertion or stress, or even lack of sleep or depression, although all of these can mimic fatigue, and may well make it worse. Depression fatigue is present associated with exhaustion on awakening with more energy as activity increases, but lack of pleasure and pessimism are clues to diagnosis.

Answered 12/4/2014

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