How can you tell the difference between sinus pressure and pressure from a brain tumor?

Pain anxiety: Sinus pressure is felt as a tight squeeze and localized generally to the area of the sinus involved. Brain tumors generally don't hurt, but the symptoms are related to the area where the lesion is located. If tumor is in the back (occipital area) of the brain, symptoms may be perceived in the eye, for example. A good physical examination may be helpful in differentiating between the two.