U.S. doctors online nowAsk doctors free
A 42-year-old member asked:

I switched from regular cymbalta to duloxetine and even though only difference is inactive ingredients, i'm having issues.. different?

2 doctor answers4 doctors weighed in
Dr. Axel Martinez-Irizarry
Family Medicine 18 years experience
Possible.: Let your doctor know about these changes, he can prescribe brand only. Insurance might make you pay a little more for brand, depending on your benefits. .Generics are just tested for bioequivalence, not efficacy. Efficacy and safety, can be expected to be essentially the same, but this is an assumption, not a fact.
Dr. Aaron Ament
59 years experience
Maybe...: I haven't run into this with duloxetine, but with some other meds. The generics are supposed to be the same but are generally manufactured by other (not the brand name) companies. They may actually not be the same. Ask you pharmacist for the name of the manufacturer of the generic and ask him/her to order you generic from a different company.

Related questions

A 32-year-old member asked:
Doctors, what is the difference between cymbalta and duloxetine?
1 doctor answer4 doctors weighed in
A 42-year-old member asked:
What are the differences between Prozac and cymbalta (duloxetine)?
2 doctor answers7 doctors weighed in
A 46-year-old member asked:
How are cymbalta and duloxetine different?
3 doctor answers6 doctors weighed in
A 44-year-old member asked:
Is duloxetine different from cymbalta? Please advise!
2 doctor answers11 doctors weighed in
Last updated Feb 25, 2022

Disclaimer:

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.