A member asked:

Difference between benefits and side effects of cymbalta (duloxetine) and zoloft?

4 doctors weighed in across 2 answers
Dr. John Moranville answered

Specializes in Psychiatry

SNRI vs SSRI: Cymbalta (duloxetine) increases serotonin and norepinephrine levels, zoloft increases serotonin levels only. Cymbala may help chronic pain as well as depression. Both are good antidepressants and have similar side effect profiles. Keep in mind there is no 1antidepressant that is effective for everyone. It may take several trials to find the right one for you or you may be lucky and respond to the 1st one.

Answered 9/29/2016

5.8k views

Thank

It would be best if your medication is managed by a Psychiatrist. If you are not confident with your doctor please see another for a second opinion.

Answered 7/27/2022

0 views

Thank

Related Questions