A 28-year-old female asked:
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4/5 results- test neg scl70, double stranded dna, ssa, ssb, smith rmp sederate, esr&crp norm, electrolyte/white/red blood norm.again + ana 1:160 centromer. what additional test to exclude scleroderma/crest?

2 doctor answers
Dr. Ed Friedlander
43 years experience Pathology
Clinical picture: Your physical exam and history should be sufficient to tell you whether you have crest. If don't have raynaud's, sclerodactyly and so forth, stop worrying. It's much more likely that your "centromere pattern" reading is a lab error than that you have smoldering crest.
Answered on Apr 11, 2014
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Dr. Hasan Noubani
35 years experience Pediatric Cardiology
UGI: An UGI is needed to rule out esophogeal motility problem.
Answered on Jun 10, 2014
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1 comment
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Dr. Tamanna Nahar
Specializes in Cardiology
Blood test for Scleroderma. But actual specific organ involvement such as the GI tract will require endoscopy.
Apr 13, 2014

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