A 28-year-old female asked:
4/5 results- test neg scl70, double stranded dna, ssa, ssb, smith rmp sederate, esr&crp norm, electrolyte/white/red blood norm.again + ana 1:160 centromer. what additional test to exclude scleroderma/crest?
2 doctor answers
Dr. Ed Friedlander answered
43 years experience Pathology
Clinical picture: Your physical exam and history should be sufficient to tell you whether you have crest. If don't have raynaud's, sclerodactyly and so forth, stop worrying. It's much more likely that your "centromere pattern" reading is a lab error than that you have smoldering crest.
Answered on Apr 11, 2014
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