A member asked:

Can you take either afrin nasal spray or sudafed nasal congestant with nyquil?

8 doctors weighed in across 3 answers

2 decongestants: Oral and nasal., not recommended try saline nasal spray to loosen congestion.

Answered 12/5/2020

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Dr. Ron Jones answered

Specializes in Family Medicine

Sparingly....: There are so many different types of nyquil. Some have decongestants, other forms of nyquil do not. Either way, I do not feel you would have a problem if afrin (oxymetazoline) used sparingly.

Answered 9/4/2018

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Dr. John Munshower answered

Specializes in Family Medicine

Yes: Either one of the the nasal sprays may be taken with nyquil.

Answered 3/25/2023

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