A member asked:

I took afrin (oxymetazoline) nasel spray for a cold this afternoon, is it safe for me to still take nyquil tonight even though it won't be 12 hours since i took afrin (oxymetazoline)?

2 doctors weighed in across 2 answers

Yes: Yes. It will be fine as long as you don't have a heart or BP condition.

Answered 8/8/2014

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Yes: Drug interaction checker shows no interactions between afrin (oxymetazoline) and nyquil.

Answered 8/8/2014

3.8k views

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