A 32-year-old female asked:
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can i take afrin nasal spray(12 hours) with nyquil together?

1 doctor answer
Dr. Arun Patel
44 years experience Family Medicine
Yes: It is not advisable to use the nose spray for more than a few days. If the conditions persist you need to see a physician
Answered on Dec 17, 2018

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Yes: But no more than 3 days, otherwise you may get addicted to the nasal spray and your nose remains congested.
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Dr. Michael Zacharisen
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Yes, short term: Oxymetazoline is a nasal decongestant spray that works quickly to decrease stuffy nose, but if used beyond 4-7 days may result in "rebound" nasal cong ... Read More

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