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A 21-year-old male asked:

If "imuran" fail to help a patient that has ulcerative colitis , so, what is the next plan for treating , is it coloctomy ?

2 doctor answers4 doctors weighed in
Dr. Donald Colantino
Internal Medicine 61 years experience
Other meds: Other effective medications are available for the treatment of ulcerative colitis which avoid having a colectomy. It is best to have a gastroenterologist manage these patients.
Dr. Jonah Essers
Pediatric Gastroenterology 18 years experience
Other drugs: If you are failing imuran (azathioprine), (azathioprine) there are several possibilities. (a) you can have your levels checked. Perhaps you need to go up on the imuran (azathioprine). (b) switch to Methotrexate (c) try Infliximab or adalimumab. Depending on where you uc is located, you might be a candidate for Mesalamine enemas, but that would only be valuable if you only have left-sided disease.

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Last updated Oct 3, 2015

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