A member asked:

Sm/rnp antibody- ana choice- positive, speckled/titer: 1:1280; sm & rnp (done alone) negative; sm/rnp antibody (together?) positive 3.0 guessing mctd?

A doctor has provided 1 answer

Dr. Ed Friedlander answered

Heads up: One of the things that's frustrating about these antibody tests looking for different connective tissue diseases is that they are difficult to do and are fraught with pitfalls. I suspect you've had at least one lab error to complicate your workup. Have you have a tube test for u1-rnp? Your clinical symptoms and signs actually tell more about your diagnosis ; best direction for treatment.

Answered 7/12/2019

4.5k views

Thank

More of what we treat

Allergies

Antibiotics

Asthma

High Blood Pressure

Prescriptions

Type 2 Diabetes

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.

Get Virtual Care

For Businesses

About Us

HealthTap Online Primary Care Doctors Accepting New Patients

A member asked:

Sm/rnp antibody- ana choice- positive, speckled/titer: 1:1280; sm & rnp (done alone) negative; sm/rnp antibody (together?) positive 3.0 guessing mctd?

A doctor has provided 1 answer

Dr. Ed Friedlander answered

Related Questions

A member asked:

Anti centromere b antibodies mine were 0.2 out of 0.0-0.9. My rnp was 1.8 out 0.0-0.9. Should i be concerned that I have mctd? The rest of ANA normal

A member asked:

Hi. Im 43 yr old female with hx juvenile arthritis at 11. Now with unexplained fever for 2 weeks. No infection. Raynauds for probably 10 years. Ana is positive and rnp igg antibodies are 1.6. All other antibodies were negative. Does this mean mctd?

A member asked:

Prime doc says positive rnp, rheumy says negative ana, and false positive for mctd. No symptoms but hashimotos. Does this sound conclusive?

A member asked:

I have had red splotches on my eyelids and under my eyes for 6-8 months. I have had a full Myositis blood panel and CBC, c1, c4 all negative but my RNP is 1.7. With only a positive RNP and not ANA rule out mctd ?

A member asked:

I had ANA labs done that show a 1:80 speckled ANA, Anti SM-RNP of 3.1, RNP of 1.1. Other labs are normal. I have no family history of autoimmune disease and currently no symptoms of MCTD. Does this indicate I have MCTD or it can develop?

Sponsored Content

People also searched for:

What could a negative ANA and positive RNP antibodies mean? I have a history of chronic rheumatological symptoms, but my dr is not convinced its MCTD.

SM/RNP 4.3, Positive ANA, Positive ENA, ANA Titer 1:1280 Speckled, Cytoplasmic Positive but low titer 1:40. Always high SED Rate and C-Reactive Protein when I am in hospital. Could this be MCTD?

I have a weakly positive ANA which show rnp antibodies...I have an extremely slow motility..Swollen fingers..Red palms..Could this be mctd?

Two years ago I had a postive ana. Recently I had a comprehensive ANA panel done and by rnp antibodies were 4.4. Could this be sle or mctd?

My rnp anti bodies was 1.8 and range the is 0.0-0.9. The rest of my ANA was neg. Besides anti centromere b was 0.2 range is 0.0-0.9. No mctd hopefuly?

Telemedicine

Primary Care

Manage Your Conditions

Women's Health

Children's Health

Men's Health

Senior Health

Wellness, Prevention & Lifestyle

Sexual Health

Mental & Behavioral Health

Travel Medicine

Urgent Care

Didn't find what you're looking for?

More of what we treat

Allergies

Antibiotics

Asthma

High Blood Pressure

Prescriptions

Type 2 Diabetes

For Businesses

Company

Health Content

Join Us

Download HealthTap

Questions?