My sister got a mammogram result of "suspicious cluster microcalcifications". is that a cancer sign?

Biopsy Needed for Dx: A mammographic report of "suspicious microcalcifications" warrants a stereotactic (nonsurgical) biopsy to definitively diagnose the abnormality. This is categorized by radiologists as a bi-rads 4 abnormality, which should be listed on the report. These are found to be cancerous approximately 15-30% of the time.

Suspicious: Microcalcification is one of the radiologic findings in breast carcinomas. The lesion can be further investigated by needle aspiration of the cells and/or biopsy so that the cells and/or tissue may be examined by a pathologist for definitive diagnosis. It is important for your sister to keep follow-up appointments to investigate the matter.

Yes biopsy best: Microcalcification can be a sign of breast cancer. There are however many calcification of the breast that are benign. Malignant type calcifications are usually tightly grouped, very small and heterogeneous in configuration. If a good mammographer is suspicious as to a group of calcifications they should be biopsied. I have seen cases of false negative MRI of breast with malignant calcification.

Yes, that: can be a sign of cancer. It needs to be biopsied. About 70% of the time that suspicious findings(BIRADS 4) are biopsied, it turns out to be benign.