No: During colonoscopy, a biopsy is performed only if there is a visible abnormality. Biopsies can lead to perforation and bleeding and should be performed only for a good indication.
Answered 12/24/2013
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Yes: It very common to take random biopsies of that part of the esophagus to look for microscopic changes that might not look abnormal to the endoscopist.
Answered 1/29/2017
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