Can you tell me how can we know if its depression or self esteem issues or laziness ?

Depression signs: Include being down most of the time, loss of interest/pleasure in activities, unintended increase/decrease in appetite/weight, sleeping more or less than usual, being agitated or lethargic, feeling worthless, inappropriately guilty or self critical, having difficulty concentrating or making decisions, ; thinking of death ; dying. Talk to your physician or a mental health professional to decide.