A member asked:

Im on effexor (venlafaxine) 200 mg and zeroquel 200 mg for depression and anxiety i want to get better i feel im getng worse. i have no confidence, no self esteem?

8 doctors weighed in across 2 answers
Dr. Marsha Davis answered

Specializes in Internal Medicine

Humph!: You probably should be in counseling with one on one. You are a very special person and there is not another person like you. You just need to find that person! you probably should visit your doctor also to be sure your meds are ok.

Answered 5/7/2016

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Add psychotherapy : You are on good medication combination, ask your psychiatrist for a change in meds if these are not effective any more. On the other hand research shows moderate to severe depression is better treated with psychotherapy in addition to medications.

Answered 5/7/2016

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