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A member asked:

A morning cup of coffee keeps me up for 24hrs+. used to be able to handle lots of caffeine but past year if i drink it i stay up all night? thoughts?

A doctor has provided 1 answer

Caffeine sensitivity: You have developed caffeine sensitivity. Caffeine blocks adenosine, which along with melatonin controls our urge to sleep. The caffeine is suppressing your Adenosine too long. As to "why", i can't say. Your Adenosine pathway must have developed a super sensitivity to caffeine at this point in time.

Dr Fowler and another doctor agreed

Answered 6/24/2014

4.8k views

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