A member asked:

What is the relationship of simvastatin that dentists us it for the treatment of gum disease?!

11 doctors weighed in across 4 answers
Dr. Gary Sandler answered

Specializes in Dentistry

Not standard of care: Simvastatin is in a class of drugs known as statins and a lipid-lowering agent that is used to lower cholesterol levels. Some studies report statins also reduced inflammation associated with gum disease which suggests that steps taken to reduce gum disease may also reduce inflammation in the arteries ; vice versa.The effects are minimal at best ; other more definitive treatment is standard of care.

Answered 2/27/2022

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None: There is no connection that i know of. But of course, there may be some new discovery that I have not heard of. Why don't you ask your doctor: " how can a cholesterol-lowering medication like simavastatin (zocor) help my gum disease?".

Answered 12/29/2014

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Dr. Jerry Hu answered

Using it?: If your cholesterol and overall cardiovascular health are improved, there can be some benefits with inflammatory response, but for 'gum' and periodontal health, the best would be to see your dentist/hygienist for routine scale, root plane, cleanings, etc. To remove tartar/ plaque, or high bacterial loads.

Answered 3/30/2014

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Inflammation: Gum disease is an inflammatory disease caused by bacteria under the gums. Simvistatin is shown to decrease certain inflammatory mediators in gum cells. I don't think it will change the fact that you will still need the normal periodontal treatment. Simvistatin alone won't cure gum disease.

Answered 10/17/2013

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