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Does zoloft cause restless leg syndrome

A 45-year-old male asked:
Dr. Daryl Tanski
Specializes in Psychiatry
Yes: Antidepressants along with other medications have been associated with worsening pre-existing restless legs syndrome or causing it.
Dr. Hanul Bhandari
Sleep Medicine 13 years experience
See below: Most selective serotonin reuptake inhibitors like zoloft (sertraline) can worsen or even initiate restless legs syndrome in some people. Have it evalu... Read More
Dr. Paul Grin
Pain Management 36 years experience
RLS: Restless legs syndrome and plmd are treated with Dopamine agonists such as ropinirole (approved in rls) or pramipexole. There are many reports in the ... Read More

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A 18-year-old female asked:
Dr. David Liu
Internal Medicine and Pediatrics 19 years experience
Yes: In general, findings of side effects related to medications are found in trials of reducing and/or stopping the medications to determine links between... Read More
A 45-year-old male asked:
Dr. Daryl Tanski
Specializes in Psychiatry
Side effect: If this side effect has persisted for several days to two weeks unfortunately it will likely persist when antidepressants cause side effects consid... Read More
Dr. Hanul Bhandari
Sleep Medicine 13 years experience
See below: Most selective serotonin reuptake inhibitors like zoloft (sertraline) can worsen or even initiate restless legs syndrome in some people. Have it evalu... Read More
A female asked:
Dr. Paul Grin
Pain Management 36 years experience
Definitely, yes: Many antidepressants such as SSRIs like Cymbalta, Effexor, (venlafaxine) and Zoloft have been linked to a worsening of RLS. Alternatives include Wellb... Read More
A 50-year-old female asked:
Dr. Bennett Werner
Cardiology 44 years experience
No: It is not a side effect of zoloft (sertraline).
A 26-year-old male asked:
Dr. Jean Yared
Specializes in Medical Oncology
See below: Gabapentin is used to treat seizure or to treat nerve pain from viruses or diabetes. There is no specific cause for restless leg syndrome, but sometim... Read More
A 22-year-old female asked:
Dr. Jeff McFadden
Family Medicine 24 years experience
Yes: Yes. Iron deficiency symptoms are associated with restless leg syndrome. If your periods are heavy, get your iron level checked and discuss options ... Read More
A 24-year-old member asked:
Dr. Emily Lu
Dr. Emily Luanswered
Family Medicine 7 years experience
Sometimes: Akisthesia (an inner restlessness that can manifest very much like restless legs syndrome) has been reported as a side effect of some antidepressants ... Read More
A 34-year-old member asked:
Dr. Alan Ali
Dr. Alan Alianswered
Psychiatry 32 years experience
RLS: Cause unknown in most cases, but it is noted to occur more in chronic kidney diseases, diabetes, iron deficiency, parkinson's disease, peripheral neur... Read More
A 51-year-old male asked:
Dr. Alfred Forrester
Psychiatry 42 years experience
Muscle spasms: A statin drug would not cause the condition known as "restless leg syndrome", but some pts taking a statin drug do report uncomfortable muscle spasms,... Read More

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

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