A member asked:

I can't stop moving my legs , can zoloft (sertraline) cause restless leg syndrome.

11 doctors weighed in across 4 answers

Yes: Antidepressants along with other medications have been associated with worsening pre-existing restless legs syndrome or causing it.

Answered 7/23/2018

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Dr. Hanul Bhandari answered

Specializes in Internal Medicine - Sleep Medicine

See below: Most selective serotonin reuptake inhibitors like zoloft (sertraline) can worsen or even initiate restless legs syndrome in some people. Have it evaluated by a sleep doctor, to check for other causes such as a low ferritin level. In some people it goes away after sometime and in some the RLS continues as long as zoloft (sertraline) is there. Discuss other options with your prescribing doctor. Also, avoid caffeine.

Answered 8/2/2019

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Dr. Paul Grin answered

Specializes in Pain Management

RLS: Restless legs syndrome and plmd are treated with Dopamine agonists such as ropinirole (approved in rls) or pramipexole. There are many reports in the literature of exacerbation of these symptoms by antidepressants (e.g.Zoloft). If tests reveal that iron levels are low iron supplementation may be prescribed. These patients may also benefit from sleep aids at night.

Answered 7/23/2018

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Dr. Hratch Karamanoukian answered

Specializes in Phlebology

Zoloft (sertraline) and RLS: Zoloft (Sertraline) increases RLS and periodic limb movements of sleep (PLM). Talk to your primary care doctor or psychiatrist who prescribed this medication.

Answered 11/28/2016

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Related Questions

A member asked:

Does sertraline give restless legs?

A doctor has provided 1 answer