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A member asked:
If taking zoloft (sertraline) can exacerbate my restless leg syndrome- does the time of day i take the meds matter? currently taking it at bedtime.
8 doctors weighed in across 2 answers
Definitely, yes: Many antidepressants such as SSRIs like Cymbalta, Effexor, (venlafaxine) and Zoloft have been linked to a worsening of RLS. Alternatives include Wellbutrin and Norpramin. Ask your doctor for more information.
Answered 10/7/2016
3.6k views
Possible: Zoloft (sertraline) usually does NOT exacerbate RLS, but if so, you might take in morning and see if that helps. Also, you might benefit from use of a dopamine agonist at bedtime to control the restless legs.
Answered 5/26/2016
1.3k views
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