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A 33-year-old male asked:

Dr syphilis clear question exposure april 1 then taken z pak 3 days course 500mg per day may 30 ,31, june 1 test rpr neg at june 2, 54 days but then thought to retest so took again after 2 more months august around 120 days rpr neg so its conclusive?

2 doctor answers2 doctors weighed in
Dr. Hunter Handsfield
Infectious Disease 55 years experience
The test result is conclusive: you do not have syphilis. However, the negative result cannot tell whether you were never infected (which is most likely) or acquired early infection that was cured by azithromycin before it had a chance to create a positive blood test. You will never know for sure, but so what? It doesn't matter now.
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Related questions

A 30-year-old male asked:
I had rapid syphilis test at week 5, RPR at week 8, rapid syph 13 week, VDRL&TPHA 16week after exposure all negative, but i have rash on hand and feet, also i consume azithromycin 500mg x 2pills at week 3, am i need retest for syphilis at week 24?
Dr. Jay Park
Dr. Jay Parkanswered
Pediatrics 52 years experience
Negative VDRL & TPHA tests at 16 weeks post exposure assure you that you were not infected.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Hunter Handsfield
Infectious Disease 55 years experience
Stop testing. You do not have syphilis and never did.
Sep 16, 2022
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A 26-year-old male asked:
Is that possible that syphilis not detected in blood test (VDRL/RPR & TPHA) 4 months after possible exposure, im a bit confuse some doctor here say 3 months are conclusive but another say take another test at 6 months?
Dr. Clarence Grim
Endocrinology 59 years experience
I would check the exact test (there several) you had and then go to CDC.gov for details for the exact test(s) you have had.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Hunter Handsfield
Infectious Disease 55 years experience
Three months is plenty, and there was no need for TPHA if your VDRL or RPR test was negative.
Sep 26, 2022
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A 31-year-old male asked:
Is a negative Syphilis RPR test at 6 weeks and 8 weeks post exposure considered a conclusive result?
Dr. Gurmukh Singh
Pathology 51 years experience
More or less. If would be preferable to repeat the test a 6 months after exposure. For healthy diet: http://www.choosemyplate.gov/., exercise 30 minut... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 46-year-old male asked:
Is a negative HIV 4th gen DUO test at 8 weeks post potential exposure conclusive? What about a negative syphilis RPR test at 8 weeks?
Dr. Hunter Handsfield
Infectious Disease 55 years experience
The AgAb (4th generation) HIV tests for sure are conclusive any time after 6 weeks. Precise data actually do not exist for RPR, even though RPR and it... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 32-year-old male asked:
Hi doctor I had my syphilis test (RPR serum) after 18 month's of exposure and the result was not reactive, Is it conclusive. Any further test required?
Dr. Hunter Handsfield
Infectious Disease 55 years experience
Yes, conclusive. You don't have syphilis. Don't waste money on any more tests.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Sep 25, 2022

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