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A 66-year-old female asked:
2 opinions on estradiol cream for vaginal atrophy. gyne prescribed it 3x a week and said risk of uterine cancer very low. my physicians assistant at my gp said i must take oral progesterone with it or my endometrium will thicken. who is right?
2 doctor answers • 2 doctors weighed in
Dr. John Berrymananswered
Obstetrics and Gynecology 56 years experience
Gradual bloodstream levels of estrogen by strictly vaginal use of estrogen sources , and can cause proliferation of endometrial cells. Long term use may be managed by your prescribing physician by occasional ultrasound imaging of the endometrial lining. If the lining is equal to one cm. in depth, a biopsy may be indicated.
Created for people with ongoing healthcare needs but benefits everyone.
Answered May 02, 2022
Dr. Hiep Leanswered
Nephrology and Dialysis 44 years experience
You should trust your GYN more.
Created for people with ongoing healthcare needs but benefits everyone.
Reviewed May 03, 2022
Related questions
A 46-year-old female asked:
Emirita makes a new estradiol cream, I have tried their progesterone cream with no benefits, would the estradiol cream be worth trying?
Dr. Alan Pattersonanswered
Obstetrics and Gynecology 44 years experience
No: Please see your gyn so you can get your hormone levels checked by blood work-not saliva like some people do and your gyn can prescribe what hormones y... Read More
Created for people with ongoing healthcare needs but benefits everyone.
4.9k viewsAnswered >2 years ago
A 36-year-old female asked:
Was given topical Estrace cream for vaginal atrophy.I'm 36.Is this safe or will it cause breast and other cancers?I take birth control.Should I stop?
Dr. Ralph Bolinganswered
Obstetrics and Gynecology 41 years experience
No: the level of estrogen is low in the creme, and not nearly as strong the estrogen in the birth control pill.
The creme form of estrogen is chemically ... Read More
Created for people with ongoing healthcare needs but benefits everyone.
472 viewsReviewed >2 years ago
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A 45-year-old member asked:
I've been diagnosed with adenomyosis. Doctor has me on natazia (estradiol valerate and dienogest). Would progesterone only pills be more beneficial for me?
Dr. Michael Traubanswered
Fertility Medicine 21 years experience
Unsure: Adenomyosis does not respond to medical treatment like other problems do. Medicine is very unpredictable. Lots of things can be tried and combined and... Read More
Created for people with ongoing healthcare needs but benefits everyone.
5.3k viewsAnswered >2 years ago
A 30-year-old female asked:
Hello, I was prescribed progesterone capsules for oral use. However my doctor said to insert them into the vagina for closer and better absorption.
Dr. Britton Crigleranswered
Obstetrics and Gynecology 14 years experience
Short cervix: Vaginal progesterone is commonly prescribed for patients with cervical incompetence or a short cervix in pregnancy. There are compounding pharmacies t... Read More
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3.1k viewsReviewed >2 years ago
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A female asked:
I was prescribed estrace (estradiol) vaginal cream to apply externally. My libido, that I thought I lost returned. Is this normal, and will it last.
Dr. Claudette Andersonanswered
Specializes in Gynecology
Yes: Part of your lack of libido apparently was due to genital changes , usually dryness ,which makes sex unpleasant.If you continue it should .
Created for people with ongoing healthcare needs but benefits everyone.
3.7k viewsAnswered >2 years ago
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Last updated May 3, 2022
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