IL
A 66-year-old female asked:
66 years old and 14 years post menopausal. for vaginal atrophy and urethral burning do i need to take oral progesterone along with estradiol .01% cream taken 3x a week. and how long can i safely use the estradiol externally?
2 doctor answers • 2 doctors weighed in

Dr. Harold Fieldsanswered
Family Medicine 63 years experience
As long as you take the dual combination you are safe.At the age of 66 you may be advised to take a drug holiday. WhatI mean discontinue
the medication for a month and if the symptoms fail to appear or are much less you may continue with no drugs. Good Luck
Created for people with ongoing healthcare needs but benefits everyone.
Answered May 02, 2022

Dr. Donald Colantinoanswered
Internal Medicine 63 years experience
If you still have a uterus, I believe it's recommended that you also take oral progesterone if you use topical estrogen to avoid continually stimulating the uterine lining which is a risk factor for endometrial cancer. Your gynecologist can advise you best,however.
Created for people with ongoing healthcare needs but benefits everyone.
Answered May 03, 2022
Last updated May 3, 2022
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