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A 23-year-old male asked:

I had an unsafe exposure 2 years ago. have heard that sometimes rpr (syphilis) can show negative 6 months after exposure but tpha can show positive. so, how to avoid false negative and how reliable is rpr 6 months after exposure. need for retesting ?

2 doctor answers3 doctors weighed in
Dr. Hunter Handsfield
Infectious Disease 54 years experience
You also asked about prozone: see that reply. False negative results are exceedingly rare for either HIV or syphilis testing, and would not occur on multiple tests. You can be certain you have neither HIV nor syphilis. Stop worrying about it! (Don't confuse guilt or shame over a sexual decision you may regret with infection risk from that event. They aren't the same.) Stop asking on this forum.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Gurmukh Singh
Pathology 50 years experience
If the HIV test and TPHA tests were negative 2 years after an exposure, you do no have either infection. For healthy diet: http://www.choosemyplate.gov/., exercise 30 minutes/day, drink enough water daily so your urine is mostly colorless, have safe sex, no tobacco alcohol weed or street drugs. Get HPV, Flu and Covid vaccines. Wish you good health!
Created for people with ongoing healthcare needs but benefits everyone.

Related questions

A 31-year-old male asked:
Is a negative Syphilis RPR test at 6 weeks and 8 weeks post exposure considered a conclusive result?
Dr. Gurmukh Singh
Pathology 50 years experience
More or less. If would be preferable to repeat the test a 6 months after exposure. For healthy diet: http://www.choosemyplate.gov/., exercise 30 minut... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 29-year-old male asked:
HIV & Syphilis testing question. Is a negative HIV RNA test and negative Syphilis RPR with no symptoms at 6 weeks I ost exposure conclusive?
Dr. Hunter Handsfield
Infectious Disease 54 years experience
The syphilis result is conclusive. The HIV result probably is as well, but RNA testing can miss a small percentage of infections. For truly conclusive... Read More
Created for people with ongoing healthcare needs but benefits everyone.
View all answers
A 29-year-old male asked:
I got a negative rpr test 3 weeks after exposure. Am i safe with syphilis?
Dr. Ed Friedlander
Pathology 45 years experience
Probably: Repeat it at eight weeks. It's not a bad idea for a guy with a social life to get checked for HIV and syphilis yearly. If the syphilis test turns up p... Read More
Created for people with ongoing healthcare needs but benefits everyone.
A 26-year-old male asked:
I had a negative RPR for syphilis at 97 days post exposure. Is this conclusive?
Dr. Hunter Handsfield
Infectious Disease 54 years experience
Yes, conclusive: The rapid plasma reagin (RPR) test is conclusive any time 6 weeks or more after the last possible exposure to syphilis.
Created for people with ongoing healthcare needs but benefits everyone.
A 31-year-old male asked:
Is Syphilis RPR and HIV 4th Gen 1/2 test negative after 8 weeks post exposure conclusive?
Dr. Gurmukh Singh
Pathology 50 years experience
No. Negative is better than positive, but to be sure you should repeat the test at 6 months after exposure. For healthy diet: http://www.choosemyplate... Read More
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Jul 20, 2022

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