India
A 33-year-old male asked:
Would a 2-1-1 (on demand) prep, in which 2 tabs of truvada before sex exposure and 1 tab for next 2 days after exposure, increase the window period for 4th gen hiv test? if yes then when would be the best period for conclusive testing? thanks?
1 doctor answer • 2 doctors weighed in

Dr. Hunter Handsfieldanswered
Infectious Disease 54 years experience
Unlike PEP, no data have been published on PrEP and delay of positive test results if it doesn't work. Logically, it shouldn't delay conclusive testing by more than a few days, maybe a week.
Reviewed Mar 19, 2021
Similar questions
India
A 33-year-old male asked:
Hi Dr. Would a 2-1-1 (on demand) PrEP, in which 2 tabs of Truvada before sex exposure and 1 tab for next 2 days after exposure, increase the window period for 4th gen HIV test? if yes then when would be the best period for conclusive testing? Thanks?
1 doctor answer • 2 doctors weighed in

Dr. Yvette Kratzberganswered
Pediatrics 25 years experience
CDC guidelines for PrEP and HIV testing in high risk patients is as follows: Daily PrEP medication use (1 tablet daily) and HIV testing every 3 months. It is not enough to use the PrEP formulation as you have described. If you are having high risk sex, use IV drugs or other high risk behaviors, you should be tested every 3 months.
Reviewed Mar 20, 2021
Last updated Mar 19, 2021
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