I am menopausal and have been prescribed a low dose of progesterone to help with hot flashes, vagina dryness and mood changes. is this safe?

It can be: Known situations that make it unsafe include past blood clotting disorder, history of breast or endometrial cancers, endometriosis, fibroids, liver problems or elevated triglycerides (type of cholesterol). Common adverse effects: nausea/bloating, breakthrough vaginal bleeding, weight gain, mood swings, breast tenderness. That said, considered safe if cautious and very effective for hot flashes.