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A member asked:
Safe to combine 5-htp with pristiq (desvenlafaxine)?
7 doctors weighed in across 2 answers
Not safe generally: T-htp is the precursor for serotonin in your body. Pristiq (desvenlafaxine) is a serotonin-norepinephrine reuptake inhibitor. Both of them can cause excess serotonin in your body which can lead to serotonin syndrome, a potentially dangerous illness. Symptoms include agitation, confusion, fever, unstable blood pressure, rapid heart rate, tremors, cramping, overactive reflexes, diarrhea, vomiting and flushing.
Answered 10/21/2017
4.8k views
Agree w Dr. Cho: This combination may increase risk of Serotonin Syndroem. Don't recommend.
Answered 11/27/2017
505 views
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