Afrin (oxymetazoline) during third trimester.. is it safe to take?

Afrin (oxymetazoline): Afrin (oxymetazoline) is fda pregnancy category c. Drugs.Com defines category c as “animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.” thus discuss with your ob/physician to determine if benefits outweigh risks.