What symptoms make langerhans cell histiocytosis the most likely diagnosis?

Bone and skin change: In Langerhans cell histiocytosis, excess immune system cells, the Langerhans cells build up . These cells, which help regulate the immune system, are normally found in the skin, lymph nodes, spleen, lungs, liver, and bone marrow. In histiocytosis, excess immature cells usually form tumors called granulomas. When granulomas develop in the bones, they cause pain, swelling and Fx.