I get random big toe pain. what should i do?

See a doctor: I would keep a diary of when the pain occurs and what shoes you are wering and what activity you are doing and then see a doctor.

Seek help: Random big toe pain if severe can mean you are having a gout attack. Usually comes on overnight. See your internist or foot specialist.

Depnds on the cause: Your pain could be as a result of many different things. A thorough history and physical exam and possibly some laboratory and radiology exams are needed to determine the exact cause. Causes of pain may include: trauma (fracture, sprain, arthritis), infection, metabolic conditions (gout), musculoskeletal or biomechanical abnormality and neurologic conditions (neuropathy).