A member asked:

After 5 da.bactrim-toe actinobacter-er for chest-neg. er md refused bactrim-off 2 da. given cipro (ciprofloxacin) after bad rxn to doubled bactrim. now not improving-did bug become resistant? new culture/sensit nec.?

2 doctors weighed in across 2 answers
Dr. Vadim Glukh answered

Specializes in Orthopedic Foot and Ankle Surgery

Multiple bugs ?: Bactrim and Cipro (ciprofloxacin) may act differently, and their spectrum may cover various bacteria. New c+s would help.

Answered 6/24/2014

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Do new C&S: When patients do not respond to antibiotics, it is time to do a culture and sensitivity....Even if one was done prior to taking the antibiotics. If pcp or other doc is having difficulty getting infection to resolve it is time to consult an infectious disease specialist.

Answered 9/25/2013

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