What can i do if my grandfather has sciatica in the leg, any relief for it or suggestions?

Sciatic pain: The sciatic pain can be caused by spinal stenosis, ruptured disc, nerve impingement ... The treatment depends on the cause of the pain. You should seek help from a health care provider, you might benefit from a comprehensive evaluation.

Sciatica: Meds, exercise, physical therapy including mckenzie centralization techniques, traction, inversion table. Many things are used.

Spine Pain Options: This pain in the distribution as you suggested is the result of an irritated nerve or facet joints or other injury typically in the lumbar spine (low back) which are caused by herniated disks, spinal stenosis or degenerative disc disease, etc requiring further evaluation by a spine specialist and may be candidate for facet injections/radiofrequency ablation and epidural steroid injection.