Bronchoscopy with biopsy of lung nodules was done, biopsy result shows normal bt bronchial washing shows poorly differentiate cancer, confused?

Second opinion: Bronchial brushing cytopathology and bronchoscopic biopsies are different and complementary techniques, so if one is negative the other can still be positive. So it sounds as if you have cancer, i'm sorry to say. It would make sense to ask for second opinions on the pathology and cytology to be sure. Don't drag this out--prompt treatment gives you a best chance for a good response & longer life.

Sample and target: You do biopsy, brushings, and washes to increase chance of diagnosis. Many forms of bronchoscopy biopsies are somewhat blind. Nodules can be tricky to "hit". It is possible to take biopsies that do not "hit the target" or nodule/tumor. It's important that you have a comprehensive thoracic oncology team approach to care for both diagnosis and treatment.

See below: I'm not sure how your procedure was done, but nodules can be very difficult to biopsy, depending on size and if any type of imaging guidance is used. So in your case, the biopsy may have only gotten normal lung tissue and the nodule itself wasn't biopsied. The washing gets a large area - normal tissue and where the nodules are. It is sent for cytology. the Biopsy would be for histology.