A member asked:

I've had psoriasis for ~15 years but it's gotten worse. i've applied betamethasone but topical is becoming impractical. are there other options?

A doctor has provided 1 answer
Dr. Robert Lowe answered

Specializes in Pediatric Rheumatology

Methotrexate, Enbrel (etanercept): Psoriasis is an autoimmune disease involving the white blood cells attacking the skin as if it was bacteria or a virus.Low dose weekly Methotrexate is very effective in treating psoriasis--the way it works is not completely understood but decades of use show it is a reliable and safe drug (no alchohol! while taking). Enbrel (etanercept) is a newer highly effective drug that neutralizes tnf, inflammatory protein.

Answered 2/10/2017

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