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A 47-year-old female asked about a 74-year-old male:

Had two big surgeries for melanoma. had iv chemo and radiation. now back. non-localized in abdomen and left kidney. chemo & radiation not option. help?

3 doctor answers8 doctors weighed in
Dr. Sewa Legha
Medical Oncology 50 years experience
New Meds for Melanom: You may benefit from a second opinion as there are now several new medicines available to treat metastatic melanoma. Some of them are immunotherapy based drugs. Actually 4 new drugs(all non -chemotherapy drugs) have been approved just during the last 2 years. So you will benefit from seeing a melanoma specialist and explore if you might be able to receive these new drugs. Good luck.
Dr. Thomas Fiala
Plastic Surgery 33 years experience
Seek an opinion: From a university center or other cancer hospital. Have their "tumor board" review your melanoma treatment so far, and see what other options (hyperthermia, immunotherapy, different chemo, etc) are available.
Dr. Michael Sabel
Surgical Oncology 29 years experience
New biologic therapy: Ask your oncologist to test the tumor for a braf mutation. Unlikely at your age but worth testing for. If the mutation is there, there at some new drugs thai may be helpful. If not, anti-ctla4 may be an option. But in all cases the risks (side effects) must be carefully weighed against the benefits. There are also some clinical trials of newer drugs that you could consider. www.cancer.gov.

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Last updated Mar 26, 2015

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