A member asked:

Should acyclovir (zovirax) 400 mg work on cold sore?

A doctor has provided 1 answer
Dr. Brian Affleck answered

Specializes in ENT and Head and Neck Surgery

Cold sore: Acyclovir is a drug used to treat herpes virus infections. Many cold sores are caused by herpes virus and will respond to such treatment. However, not all cold sores are caused by herpes. In this case, the cold sore may not respond to the treatment. The good news in all this, most cold sores get better within a couple of weeks, even without treatment. Keep it moist with ointment. This helps.

Answered 6/20/2017

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