How to get rid of penis spots?

Depends: Upon what they are and what they're due to. Someone needs to look at them and tell you. Go visit your doctor if you're concerned.

Pearly penile papule: Ring of small skin colored bumps around head of penis just beyond the circumferential groove are normal and nothing to be concerned about. These are entirely benign & usually associated or more prominent in an uncircumcised penis. You could always see a dematologist for laser treatment consultation if you really feel you can not live with them.