Can medications cause the kidneys to become atrophic?

See answer: Atrophy by definition refers to shrinking of tissue from the normal anatomical state. In that sense medications probably don't cause atrophy, but some can cause damage and loss of function. High doses of medications like nsaids and some powerful antibiotics can do this. Atrophy of the kidneys is probably more likely a result of hypertensive, ischemic (arterial narrowing) or obstructive damage.

Probably not: Kidney atrophy is usually due to long-standing kidney failure or kidney ischemia.