Could suboxone help mdd? perhaps in conjunction with other medications? how about for general anxiety and/or ptsd?

Yes, but with a cost: Suboxone can help with some subsets of depression & a proposed mechanism has been postulated. However, this is an opiate & long term use in the non-opiate dependent is not advised as it can lead to physical dependance, a bigger problem than mdd. It is used in treatment resistant depression in some european countries. Dire situations call for desperate measures; exceptions are extremely rare.

yes and no: Medical – yes: any opiates will help that. Legally – no: Suboxone is approved by fda for opioid addiction only. Fda is watching carefully and, unless addiction is present, a doctor will not likely to prescribe.

See below : It will. In fact, alkermes has a Buprenorphine combo drug under study for this reason. A doc is allowed to prescribe Suboxone off label for this purpose and I have seen it done several times. I'm fact any doctor can do this. As long as it is not for addiction, one does not even need a waiver. The problem is a lack of familiarity that most docs have with the meds and the regs.

No Suboxone with alcohol.: First of all, let's get one thing straight. You are wiping out the effects of your zoloft (sertraline) with the amount of alcohol you are drinking. I realize to you this may seem like a trivial amount but it is not. Serotonin receptors will simply not tolerate that amount of alcohol when you are taking zoloft (sertraline). All it takes to get the serotonin working when you are on zoloft (sertraline) is two drinks of alcohol. You have wiped out the next 72 hours of effectiveness. I realize that you have posttraumatic stress disorder. Living with that can be quite difficult. Substances of abuse however are not the answer. I do not have any particular problem with low-dose benzodiazepines for the anxiety that ptsd can cause, even though studies have shown that benzodiazepines are not effective for the primary symptoms of ptsd, they can be effective for generalized anxiety and panic that often accompanies the trauma. To my knowledge Suboxone has not been studied for major depressive disorder. I don't foresee it ever being studied for that at least in this country. It has been studied in germany and russia for the treatment of alcoholism. While not approved in those countries it is occasionally used there for that purpose. I think you should start working hard in therapy and using alternative therapies as well to rid yourself of substances of abuse. The only served further numb your emotions and prevent you from dealing with the trauma head on the need to deal with in order to stop being enslaved by this condition. Please to not forget diet, exercise, meditation, spiritual centering, support groups, yoga, acupuncture, and the myriad other available treatments that there are for posttraumatic stress disorder. Your primary psychotherapy should include em dr as well. Dig into your own spiritual and psychological resources to move on in life and leave this episode behind. Remember that ptsd itself is like a drug. It has a tendency to draw us back in old the scenarios that we are all too familiar with but that are not healthy for us. Seek out a substance-abuse counselor for this perspective if you have to as well. Gods speed to you as you continue on your journey of recovery.