A 48-year-old member asked:
Is it true that you shouldn't take ibuprofen if you are on zoloft (sertraline)?
3 doctor answers • 9 doctors weighed in
Dr. Andrew Oswarianswered
Family Medicine 26 years experience
Technically: Technically there is an interaction between nsaids and zoloft. Celebrex (celecoxib) is safe to take with it though.
Created for people with ongoing healthcare needs but benefits everyone.
6.1k viewsReviewed >2 years ago
Dr. Peter Corradoanswered
Family Medicine 43 years experience
Yes: Zoloft (sertraline) may increase the side effects of Ibuprofen leading to increased bleeding. In addition, Ibuprofen may decrease the effectiveness of zoloft (sertraline). Not a good combination.
Created for people with ongoing healthcare needs but benefits everyone.
6.1k viewsReviewed >2 years ago
Dr. Kevin Naskyanswered
Psychiatry 18 years experience
Not necessarily.: In general, not a problem to take both. I believe there is a moderate risk of gastrointenstinal bleeding when both ssris and nsaids are taken chronically (i.e. Every day), though i don't think there's any research showing significant risk of occasional NSAID use in patients taking ssris. It would be important to know what other GI bleeding risks you have, if any.
Created for people with ongoing healthcare needs but benefits everyone.
6.1k viewsReviewed >2 years ago
Last updated Jun 27, 2017
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