What side effects has sunitinib in treatment for renal cancer?

Sunitinib: This drug may be associated with severe/fatal liver toxicity. It may produce chf, heart attack, irregular heart rhythms, blood clots, hemorrhage, low blood cell counts (neutrophils & thrombocytes). However the benefits against renal ca may well outweigh the risks. Your oncologist will no doubt monitor liver and other functions very closely to prevent complications.

Variable: Common side effects include low blood counts, skin rash, mild nausea, mild diarrhea, fatigue, mouth sores, increased blood pressure, lowered thyroid function; these can be closely monitored and dose changes of sunitinib can help reducing side effects. Less common side effects include liver damage and heart issues.

Skin and gi: There can be fatigue, nausea, diarrhea and a skin reaction involving the hands and feet.

Many: Sunitinib is generally well tolerated. However, it is associated with may side effects including fatigue, diarrhea, nausea, anorexia, hypertension, a yellow skin discoloration, hand-foot skin reaction, and stomatitis, and in some cases heart problem. In renal cancer studies, the doses were reduced in up to 50% of patients because of side effects.