Surgery: Stage i cancer of the kidney is treated successfully with surgery (total or partial nephrectomy). I'm assuming by targeted therapy you mean agents like sunitinib, sorafenib, axitinib, or everolimus. Those are approved for advanced cancer (stage iv). I believe there are clinical trials using them after surgery for high risk patients (stage iii) but not in stage i.
Answered 12/30/2013
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