A member asked:

Can cymbalta, famotodine, benedryl, hydroxizine or magnesium increase liver enzymes. my alt was 60 in march with a virus and started these meds in june and now my alt is 100 and ast is 60. could the medications cause the increase?

2 doctors weighed in across 2 answers
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

Yes, medication can cause hepatitis. However, we could not rule out progressive hepatitis from the initial viral infection, especially you are infected with hepatitis B or C. So in this case, steps need to be carried out for defining the etiology. I hope you have been followed by a gastroenterologist or a hepatologist.

Answered 7/16/2023

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Dr. Charles Turck answered

Specializes in Pharmacology

Most of these medications don’t affect liver enzymes. A small number of patients on Cymbalta and famotidine see a temporary, unimportant rise in liver enzymes. In very rare cases with Cymbalta, the liver levels jump up twenty times higher than normal or more, and a person would experience severe abdominal pain and a yellowing of the skin and eyes. That would be a medical emergency.

Answered 7/20/2023

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