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A member asked:
Can you please explain how acute postprandial hyperglycemia activates the coagulation cascade? will there be overt symptoms related to coagulant system activation? what lab can detect aberrant activation of coagulation system in metabolic disorder?
A doctor has provided 1 answer
Post prandial hyperglycemia is a physiologic phenomenon but for patients with type 2 DM or patients with glucose intolerance, the change in glycemia is excessive and when glycemia is too high, the coagulation cascade can be triggered into the pro-thrombotic state by studies. Please read this link if you need more info - https://e-century.us/files/ijcem/9/3/ijcem0020104.pdf. Take care.
Answered 6/12/2023
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