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A member asked:
I had an isolated positive rnp of 1.8 negative being less then 1. i have no symptoms. my doctor ran an ana based on high bone specific alkaline phos and possible celiac disease. all asymptomatic?
A doctor has provided 1 answer
Positive RNP antibody does not mean you have mixed connective tissue disease (MCTD) because test specificity is low. Positive test is not uncommon in normal people. I do not see any correlation between high bone ALP levels and + RNP antibody. Good luck.
Answered 6/2/2023
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