A member asked:

I was diagnosed with a peptic ulcer that had intestinal metaplasia, no h pylori. ive been on 3 different ppi and i sill have agonizing epigastric pain. will im turn to cancer in a year? does it actually cause pain? rest of the endo normal?

2 doctors weighed in across 2 answers
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

You may need a follow-up biopsy for ruling out the progression. You can read this article from Cleveland clinic for more info - https://my.clevelandclinic.org/health/diseases/22215-intestinal-metaplasia. Good luck.

Answered 5/14/2023

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Dr. Andrew Seibert answered

Specializes in Gastroenterology

Peptic ulcers certainly can cause pain, but the treatment usually makes the pain improved after a week or two. If you are on adequate therapy and still having pain, you should be reevaluated by your Gastroenterologist BBB to see if there could be any other causes in addition. If the ulcer is in the stomach, it also needs to be reevaluated by endoscopy. Good luck.

Answered 5/15/2023

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