A member asked:

Are genetic disorders always hereditary? or do they happen randomly?

A doctor has provided 1 answer

Both. There are autosomal dominant disorders that can pass parent to child. There are autosomal recessive disorders (most metabolic ones) that only pass to a child if both parents are unaffected carriers and the child gets 2 copies of the defective gene. There are some genetic disorders where from a few to more than half of cases are from a new, usually dominant, mutation.

Answered 4/20/2023

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