A member asked:

Hello doc, i want to ask the prozone phenomenon on the syphilis test only affects the vdrl test? can the tpha test be affected by the prozone phenomenon?

2 doctors weighed in across 2 answers

All serologic tests can get affected

Answered 10/21/2022

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Visit this site for information on this topic: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139290/#:~:text=The%20prozone%20phenomenon%20refers%20to%20a%20false%20negative,immunodeficiency%20virus%20%28HIV%29%20co-infection%2C%20and%20pregnancy.%20%5B%201%5D

Answered 11/5/2022

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